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DOI: 10.1039/A900499H (Paper) Reference Section for: Chem. Commun., 1999, 1577-1578

A macromolecular Gd(III) complex as pH-responsive relaxometric probe for MRI applications

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Silvio Aime, Simonetta Geninatti Crich, Mauro Botta, Giovanni Giovenzana, Giovanni Palmisano and Massimo Sisti

Abstract

The ability of the paramagnetic macromolecular complex (GdDO3ASQ)30-Orn114 to enhance the water proton relaxation rate has been found to be a function of pH; this behaviour is related to the structural changes occurring in the polypeptide upon protonation of the side-chain NH2 groups.

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