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DOI: 10.1039/A900355J (Paper) Reference Section for: Chem. Commun., 1999, 653-654

New chemoenzymatic approach to glyco-lipopolymers: practical preparation of functionally active galactose–poly(ethylene glycol)–distearoylphosphatidic acid (Gal–PEG–DSPA) conjugate

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Samuel Zalipsky, Nasreen Mullah, Andrew Dibble and Terrence Flaherty

Abstract

A practical approach to galactose–PEG–distearoylphosphatidic acid (DSPA) retaining full lectin binding, involves glycosylation of monobenzyl ether–PEG, suitable protection of the sugar hydroxy groups, debenzylation, followed by enzymatic transphosphatidylation with phosphatidylcholine and final deprotection.

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