Stereoselective construction of the tetracyclic scalarane skeleton from carvone
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Antonio Abad, Consuelo Agulló, Ana C. Cuñat and M. Carmen Llosá
Abstract
The tetracyclic scalarane skeleton 22 has been constructed from (S)-(+)-carvone using two intramolecular Diels–Alder reactions as key synthetic steps.
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A related strategy has been previously used for the synthesis of the AB
rings of the labdane diterpene forskolin see: M. I. Colombo, J. Zinczuk and E. A. Rúveda, Tetrahedron, 1992, 48, 963 Search PubMed.
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