Synthesis and characterization of ‘calixsalens’: a new class of macrocyclic chiral ligands

Abstract

Template directed reaction of dialdehydes and (R,R)- or (S,S)-1,2-diaminocyclohexane affords a practical route to chiral, metal-free macrocyclic salen dimers which have a novel calixarene-like structure and show catalytic activity for enantioselective epoxidation of unfunctionalized alkenes in the presence of Mn^III–NaOCl (aq.).

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