DOI: 10.1039/A809435G
(Paper)
Reference Section for: Chem. Commun., 1999, 611-612
Catalytic asymmetric carbon–carbon bond forming reactions: preparation of optically enriched 2-aryl propionic acids by a catalytic asymmetric hydroboration–homologation sequence†
(Note: The full text of this document is currently only available in the PDF Version )
Austin C. Chen, Li Ren and Cathleen M. Crudden
Abstract
A new catalytic asymmetric one-carbon homologation strategy has been developed which employs a rhodium catalyzed asymmetric hydroboration followed by homologation with LiCHCl2 and oxidation to generate 2-arylpropionic acids of high enantiomeric purity.
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