DOI: 10.1039/A808347I
(Paper)
Reference Section for: Chem. Commun., 1999, 199-200
Generation of a glutathione peroxidase-like mimic using bioimprinting and chemical mutation
(Note: The full text of this document is currently only available in the PDF Version )
Junqiu Liu, Guimin Luo, Shujuan Gao, Kun Zhang, Xinfan Chen and Jiacong Shen
Abstract
Molecular imprinting of albumin with N,S-bis(2,4-dinitrophenyl)glutathione (GSH-2DNP), a glutathione (GSH) derivative, leads to an imprinted protein with GSH binding sites; chemical mutation of the protein results in formation of an artificial enzyme with high glutathione peroxidase (GPX) activity.
References
- G. Wulff, Angew. Chem., Int. Ed. Engl., 1995, 34, 1812 CrossRef CAS.
- R. A. Lerner, S. J. Benkovic and P. G. Schultz, Science, 1991, 252, 659 CAS.
- S. Saraswathi and M. H. Keyes, Enzyme Microb. Technol., 1984, 6, 98 CrossRef CAS.
- S. C. Gamble, J. Chem. Technol. Biotechnol., 1997, 68, 123 CrossRef CAS.
- O. Epp, R. Ladenstein and A. Wendel, Eur. J. Biochem., 1983, 133, 51 CAS.
- G. M. Luo, Z. Q. Zhu, L. Ding, Q. A. Sun, Z. Liu and J. C. Shen, Biochem. Biophys. Res. Commun., 1994, 198, 1240 CrossRef CAS.
- I. M. Bell, M. L. Fisher, Z. P. Wu and D. Hilvert, Biochemistry, 1993, 32, 3754 CrossRef CAS.
- D. L. Klayman and T. S. Griffin, J. Am. Chem. Soc., 1973, 95, 197 CrossRef CAS.