Sensing and amplification of oligonucleotide-DNA interactions by means of impedance spectroscopy: a route to a Tay–Sachs sensor

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Amos Bardea, Fernando Patolsky, Arie Dagan and Itamar Willner


Abstract

A three-component oligonucleotide/DNA layered assembly on a Au-electrode acts as a specific biosensor for the analysis of the Tay–Sachs mutant by means of Faradaic impedance spectroscopy.


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