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DOI: 10.1039/A807230B (Paper) Reference Section for: J. Chem. Soc., Perkin Trans. 1, 1998, 3685-3688

Synthesis of N-(protected)aminophthalimides: application to the synthesis of singly labelled isoniazid

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Nicolas Brosse, Maria-Fatima Pinto and Brigitte Jamart-Grégoire

Abstract

The synthesis of a series of N-(protected)aminophthalimides and the removal of their phthaloyl group leading to N-(protected) or N,N-bis(protected)hydrazines is described. As illustrated by the synthesis of monolabelled isoniazid 3b*, this strategy can be utilized for the preparation of monolabelled substituted hydrazines.

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