One-pot synthesis of α-amino acids based on free radical-mediated carbon–carbon bond formation

Abstract

The one-pot reaction of 2-hydroxy-2-methoxyacetic acid methyl ester with benzyloxyamine and an alkyl radical provided a convenient method for preparing the protected α-amino acids via a carbon–carbon bond formation by intermolecular carbon radical addition to glyoxylic oxime ether.

References

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