Synthesis and properties of 1-alkyl-2-methyl-3-sulfonylpyrroles and 1-alkyl-2-methyl-3-sulfonylpyrrole-5-carboxylic acid derivatives

Abstract

1,2-Dialkyl-3-sulfonylpyrroles are versatile synthetic tools for obtaining related fused ring heterocycles, for instance, pyrrolothiazines. We have established a method for obtaining pyrrolic compounds with a variety of 3-sulfonyl moieties such as sulfones 4, sulfonates 5 and sulfonamides 6.

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