Rapid and practical synthesis of D-myo-inositol 1,4,5-trisphosphate

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Shane W. Garrett, Changsheng Liu, Andrew M. Riley and Barry V. L. Potter


Abstract

A concise synthetic sequence to biologically active D-myo-inositol 1,4,5-trisphosphate is described involving just five steps from myo-inositol and minimal chromatography with a key transformation of orthoacetate into acetate protection.


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