Two-directional, convergent synthesis of a pentasaccharide that is involved in the hyperacute rejection response in xenotransplantation from pig to man

Abstract

A novel, highly convergent, regioselective glycosylation methodology based on differences in reactivity between hydroxy groups of a glycosyl donor and an acceptor has been employed for the synthesis of a pentasaccharide that is involved in the hyperacute rejection response in xenotransplantation from pig to man.

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