Synthesis of 2,5-cyclohexadien-4-one-spiro-3'-(2'-R-5',5'-dimethyl-1'-pyrrolines) by the Ritter reaction

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Vladimir A. Glushkov , Yurii V. Shklyaev , Valentina I. Sokol , Vladimir S. Sergienko and Victor V. Davidov


Abstract

Reactions of 1-(4'-methoxyphenyl)-2-methylpropene with nitriles RCN in concentrated sulfuric acid give 2,5-cyclohexadien-4-one-spiro-3'-(2'-R-5',5'-dimethyl-1'-pyrrolines) in good yields.


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