An efficient synthesis of symmetrical 2,5-diaryl-1,3,4-oxadiazoles

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Sergei I. Luiksaar , Leonid I. Belen'kii and Mikhail M. Krayushkin


Abstract

The interaction of trichloromethylarenes with excess hydrazine hydrate in alcohols leads to symmetrical 2,5-diaryl-1,3,4-oxadiazoles in 68-98% yields.


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