DOI: 10.1070/MC1998v008n04ABEH000955
(Paper)
Mendeleev Commun., 1998, 8, 153-154
On the nature of the intermediate in the Lewis acid- promoted synthesis of dihydroisoquinolines from nitriles and β-phenylethyl chloride
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Elektron A. Mistryukov and Olga N. Sorokina
Abstract
In addition to Lewis acidity, the ability to co-ordinate both reactants is a prerequisite for catalyst activity in the cyclisation reaction of β-phenylethyl chloride and alkyl- or aryl nitriles to dihydroisoquinolines.