DOI: 10.1039/A804962I
(Paper)
Reference Section for: J. Chem. Res. (S), 1998, 796-797
Facile Synthesis of Methyl 2-amino-3-(2-methyl-3-quinolyl)propanoate
(Note: The full text of this document is currently only available in the PDF Version )
Mark Hadden and Paul J. Stevenson
Abstract
Methyl 4-acetyl-5-(2-nitrophenyl)pyrrolidine-2-carboxylate 5, readily available in one step by a 1,3-dipolar cycloaddition, undergoes reduction, cyclisation and fragmentation to the corresponding quinoline when treated with hydrogen and palladium.
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