Kinetics of the Deamination of Amides by Nitrous Acid

Abstract

The kinetic profile of the rate constant for the nitrous acid–amide reaction in sulfuric acid as a function of acidity for a range of aliphatic and aromatic primary amides has been interpreted in terms of the HNO₂/NO⁺ and the amide/amide·H⁺ equilibria.

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