DOI: 10.1039/A803403F
(Paper)
Reference Section for: J. Chem. Res. (S), 1998, 530-531
Factors Affecting Facial Selectivity in the Hydroboration of Steroidal Δ5-Alkenes
(Note: The full text of this document is currently only available in the PDF Version )
Simone F. Arantes, James R. Hanson, Mansur D. Liman, Revathy Manickavasagar and Cavit Uyanik
Abstract
A comparison between the α- and β-facial selectivity observed in the hydroboration of some androst-5-enes and B-norandrost-5-enes does not parallel the difference between the calculated force field energies for α- and β-cyclobutane models suggesting that the facial selectivity is not determined by the four-centre transition state but by the relative ease of formation of the initial π-complex between the alkene and the borane.
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