Reactions with 3-Amino-5-trifluoromethyl[1,2,4]-triazole: A Convenient Route to Fluorinated Triazolo[1,5-c]thiadiazine, Triazolo[1,5-a]triazine, Thiazoles and Thiadiazoles

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Hussein F. Zohdi


Abstract

The reaction of 3-amino-5-trifluoromethyl[1,2,4]triazole with carbon disulfide or phenyl isothiocyanate followed by heterocyclization with haloketones, haloesters and hydrazonoyl halides has been utilized for the synthesis of the title compounds; chemical and spectroscopic evidence for the suggested structures of the new compounds and a sequence leading to their formation are discussed.


References

  1. R. M. Mohareb, H. F. Zohdi, S. M. Sherif and W. W. Wardkhan, Tetrahedron, 1994, 50, 5807 CrossRef CAS.
  2. R. M. Mohareb, H. F. Zohdi and W. W. Wardkhan, Monatsh. Chem., 1995, 126, 1391 CAS.
  3. H. F. Zohdi, W. W. Wardkhan, S. H. Doss and R. M. Mohareb, J. Chem. Res., 1996, (S) 440; (M) 2526 Search PubMed.
  4. H. F. Zohdi, J. Chem. Res. (S), 1992, 82 Search PubMed.
  5. H. F. Zohdi, A. H. H. Elghandour, N. M. Rateb and M. M. M. Sallam, J. Chem. Res., 1992, (S) 396; (M) 3015 Search PubMed.
  6. H. F. Zohdi, H. Y. Afefy and A. O. Abdelhamid, J. Chem. Res. (S), 1993, 76 Search PubMed.
  7. H. F. Zohdi, J. Chem. Res., 1997, (S) 392 (M) 2378 Search PubMed.
  8. A. O. Abdelhamid, S. E. Abdou and F. H. El-Shiaty, Phosphorus, Sulfur, Silicon Relat. Elem., 1994, 88, 217 CAS.
  9. H. F. Zohdi, N. M. Rateb and A. O. Abdelhamid, Phosphorus, Sulfur, Silicon, Relat. Elem., 1997, in the press Search PubMed.
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