Synthesis, Spectral Studies, In Vitro Antimicrobial and In Vivo Multi-infection Antifungal Activities in Mice of New Organotin(IV) Derivatives of Amino Acids

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Mala Nath, Rakesh Yadav, G. Eng and P. Musingarimi


Abstract

Tri- and diorganotin(IV) complexes of L-tyrosine, DL-aspartic acid and L-glutamic acid have been found to show antimicrobial activity in vitro and slight activity in vivo against a multi-infection antifungal model in mice.


References

  1. R. C. Poller, The Chemistry of Organotin Compounds, Academic Press, New York, 1970 Search PubMed.
  2. M. J. Koopmans, Dutch Pat. 96,805, 1961(Chem. Abstr., 1961, 55, 27756f) Search PubMed.
  3. D. A. Kochkin, S. G. Verenkina and I. B. Chekmareva, Dokl. Akad. Nauk, SSSR, 1961, 139, 1375 Search PubMed.
  4. H. Brückner and K. Hartel, Ger. Pat. 1,061,561 (16 July 1959)(Chem. Abstr., 1961, 55, 6772d) Search PubMed.