Simple Reduction of Various Ketones with Sodium Tetrahydroborate and Alumina in Hexane†

Abstract

A combination of NaBH₄ and alumina preloaded with a small amount of water is a highly efficient reducing agent for cycloalkanones, substituted cyclohexanones and unsaturated and aromatic ketones in hexane, affording the corresponding alcohols in excellent yields under mild conditions (20–60°C).

References

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