DOI: 10.1039/A708521D
(Paper)
Reference Section for: J. Chem. Res. (S), 1998, 330-331
Improved Synthesis of 2-Amino-3-cyanopyridines in Solvent Free Conditions under Microwave Irradiation†
(Note: The full text of this document is currently only available in the PDF Version )
Satya Paul, Rajive Gupta and Andre Loupy
Abstract
A simple and efficient method is developed for the rapid synthesis of 2-amino-3-cyanopyridines 3–5 from arylidenemalanonitriles 1 and ketones 2 or 4 in presence of ammonium acetate without solvent/containing traces of solvent under microwave irradiation:reaction times are considerably reduced with improved yields as compared to those obtained under classical heating.
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