A Concise and Convenient Method for the Synthesis of Pure Substituted Thioureas
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K. Ramadas and N. Janarthanan
Abstract
Zinc dialkyldithiocarbamates offer excellent substrates for the pure thioureas required for antifungal and X-ray crystallographic studies.
References
K. Ramadas, N. Janarthanan and S. Velmathi, Synth. Commun., 1997, 27, 2255 CAS.
K. Ramadas, N. Srinivasan and N. Janarthanan, Tetrahedron Lett., 1993, 34, 6447 CrossRefCAS; K. Ramadas and N. Srinivasan, Synth. Commun., 1995, 25, 3381 CAS.
K. Ramadas and N. Srinivasan, Tetrahedron Lett., 1995, 36, 2841 CrossRefCAS; K. Ramadas, N. Janarthanan and R. Pritha, Synth. Lett., 1997, 1053 CAS.
D. C. Schroeder, Chem. Rev., 1955, 55, 181 CrossRefCAS.
K. Ramadas, Tetrahedron Lett., 1996, 37, 5161 CrossRef (The success of the synthesis of thioureas depends upon the elimination of
hydrogen sulfide from the reaction mixture. Triethanolamine
forms a water soluble adduct with H2S which is liberated quantitatively
by gentle warming of the acidified solution
to regenerate the tertiary amine.).
K.-Y. Jen and M. P. Cava, Tetrahedron Lett., 1982, 23, 2001 CrossRefCAS.
G. Y. Sarkis and E. D. Faisal, J. Heterocycl. Chem., 1985, 22, 137 CAS; Houben, Methoden Org. Chem. (Houben-Weyl), 1983, VE4, 843 Search PubMed; N. Yamazaki, T. Tomioki and F. Higashi, Synthesis, 1975, 384 CrossRefCAS; A. R. Katritzky and M. F. Govdeer, J. Chem. Soc., Perkin Trans. 1, 1991, 2199 RSC and all other methods cited therein.
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