Crystal Structure of 1-(3,5-Dichloro-2,4-difluorophenyl)-3-(2,6-difluorobenzoyl)urea, an Inhibitor of Chitin Synthesis

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Li Zhong, Qian Xuhong, Zhu Zhixiang, Xia Zongxiang and Sun Jie


Abstract

The crystal structure of 1-(3,5-dichloro-2,4-difluorophenyl)-3-(2,6-difluorobenzoyl) urea, an inhibitor of chitin synthesis, has been established; the crystal belongs to the triclinic system but with Z=6 and there are three molecules of different conformations in each asymmetric unit; the urea linkage was coplanar for the formation of an intramolecular hydrogen bond.


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