Novel Synthesis of Thioguanine and Sulfanylpurine Analogues: Reaction of Heterocyclic Ketene Dithioacetals with Nucleophiles

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Galal H. Elgemeie, Ahmed H. Elghandour, Ali M. Elzanate and Sayed A. Ahmed


Abstract

A novel synthesis of thioguanine and sulfanylpurine analogues via the reaction of heterocyclic ketone dithioacetals with nucleophiles is reported and the synthetic potential of the method is demonstrated.


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