Synthesis of Diversely Functionalised Dibenzylbutyrolactones and Aryltetralins from Silylated Cyanohydrin Anions

(Note: The full text of this document is currently only available in the PDF Version )

Robert S. Ward, Andrew Pelter, Antonella Brizzi, Alessandro Sega and Paola Paoli


Abstract

The aryltetralins 7a and 7b and the keto-lactone 8 are synthesised by cyclisation and deprotection of the conjugate addition products 4a and 4b; the structure of 7b was unambiguously confirmed by an X-ray structural analysis.


References

  1. T. Ogiku, S. Yoshida, M. Takahashi, T. Kuroda, H. Ohmizu and T. Iwasaki, Tetrahedron Lett., 1992, 33, 4473, 4477 CrossRef CAS.
  2. T. Ogiku, S. Yoshida, T. Kuroda, M. Takahashi, H. Ohmizu and T. Iwasaki, Bull. Chem. Soc. Jpn, 1992, 65, 3495 CAS.
  3. Y. Moritani, C. Fukushima, T. Ogiku, T. Ukita, T. Miyagishima and T. Iwasaki, Tetrahedron Lett., 1993, 34, 2787 CrossRef CAS.
  4. A. Pelter, R. S. Ward and N. P. Storer, Tetrahedron, 1994, 50, 10829 CrossRef CAS.
  5. J. P. Kutney, M. Arimoto, G. M. Hewitt, T. C. Jarvis and K. Sakata, Heterocycles, 1991, 32, 2305 CAS.
  6. J. P. Kutney, Y. P. Chen, S. Gao, G. M. Hewitt, F. Furi-Brena, R. K. Milanova and N. M. Stoynov, Heterocycles, 1993, 36, 13 CAS.
  7. J. P. Kutney, X. Du, R. Naidu, N. M. Stoynov and M. Takemoto, Heterocycles, 1996, 42, 479 CAS.
Click here to see how this site uses Cookies. View our privacy policy here.