DOI: 10.1039/A702638B
(Paper)
Reference Section for: J. Chem. Res. (S), 1998, 30-31
The Reaction of Ethyl 2-Chloroacetoacetate with 2-(Alkylamino) Alcohols: an Unexpected Formation of the 2-Methyloxazolidine Ring†
(Note: The full text of this document is currently only available in the PDF Version )
Lubomir Nechev, Alexander Dobrev, Ivailo Ivanov and Tzvetanka Cholakova
Abstract
The reaction of 2-(alkylamino) alcohols and ethyl 2-chloroacetoacetate in the presence of sodium alkoxides proceeds with unexpected formation of 2-hydroxy-2-(2-methyloxazolidin-2-yl)acetic esters instead of the aza analogues of carboxin (5,6-dihydro-1,4-oxazines) as previously reported in the literature.
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