DOI: 10.1039/A807506I
(Paper)
Reference Section for: Chem. Commun., 1998, 2481-2482
The effect of strain on reactivity: poor leaving groups increase strain-induced inhibition of alkene-forming elimination
(Note: The full text of this document is currently only available in the PDF Version )
Luca Volta and Charles J. M. Stirling
Abstract
Elimination to form a carbon–carbon double bond exocyclic to a cyclopropane ring is inhibited by factors which increase from 1.4 to 104.5 as the leaving group becomes poorer; strain induced in the transition structure can amount to some 50% of the enthalpy difference between strained and unstrained products.
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