The biosynthesis of pramanicin: intact incorporation of serine and absolute configuration of the antibiotic

Abstract

Biosynthetic incorporation of isotopically labelled serines into pramanicin 1 in Stagonospora sp. ATCC 74235 shows that L-serine is incorporated as an intact entity with all four bonds to the α-carbon retained; thus 1 is assigned the 5S absolute configuration.

References

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