DOI: 10.1039/A806236F
(Paper)
Reference Section for: Chem. Commun., 1998, 1995-1996
A new route to functionalised π-allyltricarbonyliron lactam complexes from aziridines and their use in stereoselective synthesis and oxidative conversion to β-lactams
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Steven V. Ley and Ben Middleton
Abstract
Aziridinyl enones can be converted in good yield into π-allyltricarbonyliron lactam complexes bearing ketone functionality in the side chain; addition of a variety of nucleophiles into the side chains of these complexes proceeds in good yield and excellent (>95%) de to afford secondary and tertiary alcohols which on treatment with trimethylamine N-oxide form the corresponding β-lactams in good yield.
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