Hydrophobic proteins: synthesis and characterisation of organic-soluble alkylated ferritins

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Kim K. W. Wong, Nicola T. Whilton, Trevor Douglas, Stephen Mann and Helmut Cölfen


Alkylated derivatives of the iron storage protein, ferritin, have been prepared by carbodiimide-activated coupling of long chain primary amines to surface carboxylic acid residues; the proteins are soluble in dichloromethane as intact, non-aggregated biomolecules.


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