Ultra rigid cross-bridged tetraazamacrocycles as ligands—the challenge and the solution

Abstract

The challenge to metal ion binding that is represented by the proton-sponge nature of two-carbon cross-bridged tetraazamacrocycles has been overcome and a general method developed for the synthesis of their transiton, and other, metal complexes; these ultra-rigid ligands form complexes having remarkable kinetic stabilities.

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