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DOI: 10.1039/A801722K (Paper) Reference Section for: Chem. Commun., 1998, 1045-1046

Tropic acid biosynthesis: the incorporation of (RS)-phenyl[2-18O,2-2H]lactate into littorine and hyoscyamine in Datura stramonium

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Chi W. Wong, David O’Hagan, Chi W. Wong, John T. G. Hamilton, David O’Hagan, Richard J. Robins and Richard J. Robins

Abstract

The incorporation of oxygen-18 from (RS)-phenyl- [2-18O,2-2H]lactate into the tropane alkaloids littorine 1 and hyoscyamine 2 in Datura stramonium reveals that up to 29% of the oxygen-18 is lost during the transformation of 1 to 2.

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