Formation of 1,11-bis(pendant donor)-cyclam derivatives via the formamidinium salt (cyclam = 1,4,8,11-tetraazacyclotetradecane)

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Philip J. Davies and Max R. Taylor


Abstract

When reacted in chloroform, the dimethyl acetal of dmf and cyclam (1,4,8,11-tetraazacyclotetradecane) forms a stable formamidinium salt which can be used as an intermediate for very simple formation of 1,11-bis(pendant donor)-cyclam derivatives.


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