Ochratoxin A acts as a photoactivatable DNA cleaving agent

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Ivan G. Gillman, Jennifer M. Yezek and Richard A. Manderville


Abstract

The ability of ochratoxin A to photoinduce DNA cleavage is described; in the presence of DNA the photoreaction yields the non-chlorinated derivative, ochratoxin B, while a hydroquinone derivative is produced under anaerobic conditions.


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