Stereoselective synthesis of a new optically active phosphinoacyloxazolidinone via enantioselective hydrogenation

Abstract

The preparation of a new optically active phosphinoacyloxazolidinone, based on the enantioselective hydrogenation of a 4-methylene-N-propionyloxazolidinone in the presence of [(R)-BINAP]Ru(O₂CCF₃)₂ catalyst followed by stereoselective phosphinylation, is reported.

References

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