Pierre Le Gendre, François Jérôme, Christian Bruneau and Pierre H. Dixneuf
The preparation of a new optically active phosphinoacyloxazolidinone, based on the enantioselective hydrogenation of a 4-methylene-N-propionyloxazolidinone in the presence of [(R)-BINAP]Ru(O2CCF3)2 catalyst followed by stereoselective phosphinylation, is reported.