Either γ-syn- or γ-anti-selective palladium-catalysed carbonyl allylation by mixed (E)- and (Z)-1,3-dichloropropene with tin(II) halides

Abstract

Palladium-catalysed carbonyl allylations by mixed (E)- and (Z)-1,3-dichloropropene with SnI₂–Bu₄NI and SnCl₂ diastereoselectively produce syn and anti 1-substituted 2-chlorobut-3-en-1-ols, respectively. These are transformed into cis and trans 1-substituted 2-vinyl epoxides.

References

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