New synthetic methodology utilising 1,2-dioxines and stabilised phosphorus ylides: a highly diastereoselective cyclopropanation reaction

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Thomas D. Avery, Thomas D. Haselgrove, Dennis K. Taylor, Edward R. T. Tiekink, Thomas D. Avery and Tanya J. Rathbone


Abstract

A new method is described for the synthesis of diastereomerically pure cyclopropanes from substituted 1,2-dioxines 1a–c and stabilised phosphorus ylides 2a–e.


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