Asymmetric aldol reaction of 2-cyanopropionates catalysed by trans-chelating chiral diphosphine ligand TRAP–rhodium(I) complex

Abstract

trans-Chelating chiral diphosphine TRAP ligands bearing P-aromatic groups are effective for Rh^I-catalysed asymmetric aldol reaction of 2-cyanopropionates with an aldehyde to give the corresponding aldol adduct with up to 93% ee.

References

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