Sc(OTf)3-Catalyzed three-component reactions of aldehydes, amines and allyltributylstannane in micellar systems. Facile synthesis of homoallylic amines in water

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Shū Kobayashi


Abstract

Three-component reactions of aldehydes, amines and allyltributylstannane proceeded smoothly in water without using any organic solvents, in the presence of a small amount of scandium trifluoromethanesulfonate [Sc(OTf)3] and sodium dodecylsulfate (SDS), to afford the corresponding homoallylic amines in high yields.


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