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DOI: 10.1039/A706211G (Paper) Reference Section for: Chem. Commun., 1998, 427-428

Highly efficient synthesis of phosphorodithioates derived from 3′-thiothymidine by anhydro-ring opening of 2,3′-anhydro-5′-O-tritylthymidine with O,O-disubstituted phosphorodithioic acids

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Wojciech D[a with combining cedilla]bkowski, Izabela Tworowska, Wojciech D[a with combining cedilla]bkowski and Maria Michalska

Abstract

Thymidine 3′-S-phosphorodithioate 4 and dithymidine-3′-S-phosphorodithioate 7 derived from 3′-thiothymidine are synthesized in excellent yield under mild conditions by the nucleophilic ring opening of 2,3′-anhydrothymidine with phosphorodithioic acids.

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