PerspectiveDo we really need detection limits?

Abstract

Detection limits cause problems for analytical chemists because they are difficult to interpret and because the arbitrary dichotomising of the concentration domain provides a misleading viewpoint of the behaviour of analytical systems. A joint consideration of uncertainty of measurement and fitness for purpose could avoid these problems.

References

1. Analytical Methods Committee, Analyst, 1987, 112, 199.
2. Detection in Analytical Chemistry, ed. Currie, L. A., American Chemical Society, Washington, DC, USA, 1988, pp. 1–335.
3. Guide to the Expression of Uncertainty in Measurement, International Standards Organization, Geneva, Switzerland, 1993.
4. Quantifying Uncertainty in Analytical Measurement, Eurachem, Laboratory of the Government Chemist, Teddington, UK, 1995.
5. Analytical Methods Committee, Analyst, 1995, 120, 2303.
6. M. Thompson and T. Fearn, Analyst, 1996, 121, 275.