Annemieke Madder, Pierre J. De Clercq and Howard Maskill
Enforced intramolecular hydrogen bonding facilitates intramolecular general base catalysis in the acetylation of a family of α,ω-amino alcohols by acetylimidazole, and the site of acetylation when there are two hydroxy groups is determined by the relative ease of intramolecular hydrogen bonding rather than by intermolecular steric effects.