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DOI: 10.1039/A704706A (Paper) Reference Section for: J. Chem. Soc., Perkin Trans. 1, 1997, 2451-2454

Development of arylhydrazines and diphenyl arylhydrazidophosphates as photo-induced DNA-cleaving agents

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Jih Ru Hwu, Chii Shyang Yau, Fu Yuan Tsai and Shwu-Chen Tsay

Abstract

Single-strand cleavage of DNA in a sodium phosphate buffer at pH 7.4 has been accomplished by photolysis of various arylhydrazines or diphenyl arylhydrazidophosphates with 312 nm UV light; the new processes involve the generation of HO˙ and singlet oxygen, respectively.

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