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DOI: 10.1039/A704312K (Paper) Reference Section for: J. Chem. Soc., Perkin Trans. 1, 1997, 3387-3392

Synthesis based on cyclohexadienes. Part 23.1 Total synthesis of 5-epi-pupukean-2-one

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Krishna Kaliappan and G. S. R. Subba Rao

Abstract

A new strategy for the construction of the isotwistane skeleton is reported from easily available cyclohexadienes which involves stereoselective alkylation of a bicyclooctenone derivative and a decarboxylative 5-exo-trig radical cyclisation as the key steps in the total synthesis of 5-epi-pupukean-2-one.

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