First diastereoselective [3+2] cycloaddition of chiral non-racemic alkenyl Fischer carbene complexes with diazomethane derivatives

Abstract

(-)-8-Phenylmenthol derived pentacarbonylalkenyl(alkoxy)chromium carbene complexes react with diazomethane derivatives to give only one diastereomer of enantiomerically pure 4,5-dihydro-1H-pyrazoles; the one-pot synthesis of the corresponding esters is also described.

References

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