DOI: 10.1039/A608207F
(Paper)
Reference Section for: J. Chem. Soc., Perkin Trans. 1, 1997, 185-186
Facilitation of displacements at the 6-position of purines by the use of 1,4-diazabicyclo[2.2.2]octane as leaving group
(Note: The full text of this document is currently only available in the PDF Version )
Nicola K. Lembicz, Sharon Grant, William Clegg, Roger J. Griffin, Sarah L. Heath and Bernard T. Golding
Abstract
Reactions of 6-chloropurines with 1,4-diazabicyclo[2.2.2]octane (DABCO) give the corresponding ‘DABCO-purines’ 1a–d, which undergo facile displacement reactions with alkoxides in dimethyl sulfoxide to afford 6-oxy-substituted purines.
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