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DOI: 10.1039/A606197D (Paper) Reference Section for: J. Chem. Soc., Perkin Trans. 1, 1997, 195-200

Synthesis based on cyclohexadienes. Part 21.1 Total synthesis of (±)-hinesol and (±)-10-epi-hinesol

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Seenivasaga N. Janaki and G. S. R. Subba Rao

Abstract

An efficient strategy for the construction of the spiro[4.5]decane and eremane systems is described which involves an acid-catalysed rearrangement of an endo alcohol, followed by an oxidative cleavage resulting in the generation of a spiro-system, as the key step. This methodology is extended to the total synthesis of (±)-hinesol and (±)-10-epi-hinesol 2.

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