Facile construction of spirobicyclic skeletons by intramolecular aldol reaction: simple formal syntheses of (±)-spirojatamol and (±)-erythrodiene

Abstract

An intramolecular aldol reaction of keto acetals 1, regioselectively performed with Me₃SiI–(Me₃Si)₂NH leading to spirobicyclic compounds 2 and 3, has been applied to the syntheses of (±)-spirojatamol and (±)-erythrodiene.

References

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