Stereoselective coupling of riboses with metallic salts of aromatic heterocycles

Abstract

The coupling of 2,3,5-tri-O-benzyl-D-ribofuranose with the magnesium, cadmium and zinc salts of typical aromatic heterocycles can afford the corresponding β-C-nucleosides stereoselectively. Furthermore, the present method can be applied to the synthesis of β-C-deoxynucleosides having N-containing aromatic heterocycles as base moieties.

References

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